The Indiana Hoosiers and Kentucky Wildcats renew their rivalry when they meet in non-conference action on Saturday. Indiana is coming off a 113-72 win over Penn State on Tuesday, while Kentucky downed North Carolina Central 103-67 that same night. The Hoosiers (8-2), who finished ninth in the Big Ten at 10-10 and were 19-13 overall last year, are 0-1 on the road this season. The Wildcats (6-4), who tied for sixth in the SEC at 10-8 and were 24-12 in 2024-25, are 6-1 on their home floor this year.
Tipoff from Rupp Arena in Lexington, Ky., is set for 7:30 p.m. ET. Kentucky is a 3.5-point favorite in the latest Indiana vs. Kentucky odds from SportsLine consensus, while the over/under for total points scored is 159.5. Before making any Kentucky vs. Indiana picks, check out the men’s college basketball predictions and betting advice from the SportsLine Projection Model.
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The SportsLine Projection Model simulates every college basketball game 10,000 times and has returned over $2,000 in betting profit for $100 players on its top-rated college basketball picks over the past three seasons. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen huge returns.
Now, the model has simulated Indiana vs. Kentucky 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for Kentucky vs. Indiana:
Indiana vs. Kentucky spread:
Kentucky -3.5 at DraftKings Sportsbook
Indiana vs. Kentucky over/under:
159.5 points
Indiana vs. Kentucky money line:
Indiana +138, Kentucky -166
Indiana vs. Kentucky picks:
See picks at SportsLine
Indiana vs. Kentucky streaming:
Fubo (Try for free)
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How to make Indiana vs. Kentucky picks
SportsLine’s model is going Over on the total (159.5 points). The over hit in three of the last four Indiana games, while the over hit in Kentucky’s last game.
The model projects the Hoosiers to have six players register 11.1 points or more, led by Lamar Wilkerson’s projected 16.5 points. The Wildcats, meanwhile, are projected to have four players scoring 10.2 or more points, led by Otega Oweh with 14 points. The model projects a combined total of 161 points as the Over clears in nearly 60% of simulations.
The model also says one side of the spread hits well over 50% of the time. You can only see that pick at SportsLine.
So who wins Indiana vs. Kentucky, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Indiana vs. Kentucky spread to back, all from the advanced model was profitable on top-ranked college basketball picks last season, and find out.
