The 2025 NFL Kickoff Game signals the return of professional football, and the defending world champions will be in action after hoisting their Super Bowl banners. The Philadelphia Eagles will host the Dallas Cowboys, and the Eagles are 8.5-point favorites, while the latest NFL odds list the over/under at 47.5 points. There are also dozens of NFL player props being offered, and alternate NFL props provide a chance to either enhance your payout or take a more risk-averse approach. For example, Dak Prescott’s over/under for total passing yards is 244.5, but if you think that he’ll be on a mission in his comeback season, you can find him to pass for 300 yards or more listed at +321 (risk $100 to win $321).
Meanwhile, Saquon Barkley rushed for 167 yards in Week 17 against the Cowboys last year, and you can get +630 for him to rush for 150 yards or more in the latest Eagles vs. Cowboys odds. NFL alternate line props are available for almost every player in every game, and you can combine them with some of the best sportsbook promos to add even more value. SportsLine’s proven computer model can help you identify some of the top NFL alt props and best NFL odds to use on some of the best sports betting apps. Use the latest DraftKings promo code, and you can get $300 in bonus bets instantly as well as over $200 off on NFL Sunday Ticket.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model went 31-15 on top-rated picks in 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.
Best NFL player prop longshots for Cowboys vs. Eagles:
Jalen Hurts, Eagles, 50+ rushing yards (+198)
With arguably the best offensive line in football, Saquon Barkley, and a mobile quarterback who runs with power, the Eagles made a concerted effort to use their running game to control the line of scrimmage last season, and it resulted in a championship. Expect more of the same in 2025, with Hurts continuing to use his athleticism as a failsafe. His over/under for total rushing yards is 36.5 yards, but we’re projecting 51.8 yards on average, and you can find him priced at +198 to record 50 or more rushing yards at FanDuel, where you can also get $300 in bonus bets if your first wager of $5 or more wins.
George Pickens, Cowboys, 70+ receiving yards (+157)
Over three seasons in Pittsburgh, Pickens flashed enormous big-play ability, but he was also inconsistent and mercurial. As a result, he was traded along with a sixth-round pick to the Cowboys for a third-round pick and a seventh-round pick in May. Now he’ll join a potentially dynamic offense with Prescott and CeeDee Lamb, where the pressure should be off to an extent as WR2. His over/under for receiving yards is 55.5, but the model projects 72.1 yards on average, so you can squeeze out some extra value from this alt line at DraftKings.
DeVonta Smith, Eagles, two or more touchdowns (+1400)
After back-to-back 1,000-yard receiving seasons, Smith missed four games in 2025 and finished with 68 catches for 833 yards. However, he did set a new career-high with eight touchdowns and led the Eagles in receiving TDs. Barkley (+325) and Hurts (+450) are technically the more likely players to score twice because of Philadelphia’s run dependence, but Smith’s the best value play here given his 25.6% red-zone target share last season and the fact that he’s scored multiple touchdowns twice in eight career regular-season games against the Cowboys. Get this price at BetMGM, where you can also get up to $1,500 in bonus bets back if your first bet loses.
Where to bet NFL alternate props for Eagles vs. Cowboys
Here is a look at sportsbooks that will offer NFL player props for NFL Opening Kickoff Game 2025:
More NFL picks for Dallas vs. Philadelphia
You’ve seen the model’s top NFL alt prop picks for the 2025 NFL Opening Kickoff Game between the Philadelphia Eagles and Dallas Cowboys. Now, get NFL projections for every player prop and NFL predictions for every game at SportsLine.
Need more from SportsLine? See the top Week 1 NFL picks from SportsLine NFL expert Sia Nejad, who is on a 64-38-2 roll (+2050) on NFL picks.
